Estrogen Dominance and the Liver: Why Glucuronidation and Sulfation Are the Hidden Bottlenecks
Estrogen dominance is often framed as “too much estrogen,” but the deeper issue is almost always poor estrogen clearance, not overproduction. The body may be making a normal amount of estrogen—yet struggling to process and excrete it through the liver, bile, and gut. When Phase I and Phase II detoxification pathways become unbalanced—especially glucuronidation (UGTs) […]






